
*******uv prolapse*******
History for a 60-Year-Old Woman with Second-Degree Uterovaginal Prolapse and Stress Incontinence
- Presenting Complaints
– Symptoms of Prolapse
– Vaginal bulge or a sensation of “something coming out.”
– Feeling of heaviness or dragging in the pelvis.
– Symptoms worsening with standing or straining and relieved by lying down.
– Symptoms of Stress Incontinence
– Involuntary urine leakage during coughing, sneezing, laughing, or physical activity.
– Frequency or urgency of urination (if present).
– Associated Symptoms
– Difficulty with voiding: incomplete emptying, weak stream, or double voiding.
– Recurrent urinary tract infections.
– Difficulty with bowel movements or constipation.
– Pelvic or lower back pain.
– Dyspareunia (painful intercourse) or vaginal dryness.
- Duration and Progression
– Onset of symptoms: when they started and how they have progressed.
– Impact on daily activities and quality of life (e.g., work, social life, and intimacy).
- Risk Factors
– Obstetric History
– Number of pregnancies, mode of delivery, history of prolonged labor, or instrumental deliveries, Perineal tear/episiotomy
– Birth weight of babies (>4 kg increases risk).
– Gynecological History
– History of menopause and postmenopausal atrophy.
– Previous gynecological surgeries, such as hysterectomy or pelvic floor repair.
– Medical and Lifestyle History
– Chronic cough (COPD, asthma, smoking).
– Chronic constipation or straining.
– Obesity.
– Heavy lifting or strenuous physical work.
– Family History
– Any family history of pelvic organ prolapse or connective tissue disorders.
- Treatment History
– Previous Interventions
– Use of vaginal pessaries and patient satisfaction with them.
– Any medications for bladder control (e.g., anticholinergics or beta-3 agonists).
– Previous physiotherapy or pelvic floor muscle training.
– Any prior surgeries for prolapse or incontinence.
- Differential Diagnosis Considered
– Pelvic Masses: Ovarian cysts, uterine fibroids.
– Bladder Disorders: Overactive bladder, urethral diverticulum.
– Other Incontinence Types: Mixed or urge incontinence.
– Rectal Prolapse or Intussusception.
- Complications of Current Condition
– Vaginal ulcers or erosions due to prolonged prolapse- Local complications- Discharge, bleeding, ulcer
– Recurrent urinary tract infections.
– Hydronephrosis or renal dysfunction in severe cases of obstruction.
– Social embarrassment, depression, or anxiety.
– Sexual dysfunction- if sexually active
- Patient Expectations
– Desire for definitive management or symptom relief.
– Preference for non-surgical versus surgical treatment.
– Concerns about post-operative recovery and risks.
– Goals related to quality of life, including mobility, independence, and sexual activity.
Examination
- General Examination
– Vital Signs
– Measure blood pressure, pulse, respiratory rate, and temperature.
– Assess for hypertension or any other systemic conditions.
– General Appearance
– Body habitus (e.g., obesity, malnutrition).
– Mobility and functional status.
– Signs of Chronic Illnesses
– Pallor (anemia), cyanosis, jaundice, or lymphadenopathy.
– Signs of connective tissue disorders (e.g., hypermobility of joints).
– Skin Examination
– Look for skin changes such as bruising (possible anticoagulant use), trophic changes, or signs of chronic illnesses.
– Edema
– Check for pedal edema, which might indicate venous stasis or systemic disease.
- Abdominal Examination
– Inspection
– Look for scars from previous surgeries (e.g., cesarean section, hysterectomy, or pelvic surgeries).
– Assess for distension, visible masses, or hernias (e.g., incisional hernia).
– Palpation
– Palpate for tenderness or masses.
– Assess for an enlarged bladder (due to incomplete voiding) or other palpable abnormalities.
– Percussion
– Assess for bladder distension or ascites.
– Auscultation
– Listen for bowel sounds, especially if constipation or abdominal pain is reported.
- Respiratory Examination
– Inspection
– Look for signs of chronic cough, barrel chest, or other indications of chronic obstructive pulmonary disease (COPD).
– Assess for use of accessory muscles of respiration.
– Palpation and Percussion
– Evaluate for resonance and chest wall tenderness.
– Auscultation
– Assess for wheezing, crackles, or decreased breath sounds that may indicate chronic bronchitis, emphysema, or other pulmonary conditions.
Note: Chronic cough can exacerbate prolapse symptoms and should be addressed as part of management.
- Central Nervous System Examination
– Mental Status
– Assess orientation, memory, and cognition, especially if incontinence has affected mental well-being.
– Motor Examination
– Assess lower limb strength and mobility, as pelvic floor dysfunction may coexist with neurologic issues.
– Reflexes
– Check for bulbocavernosus and anal reflexes to assess sacral nerve integrity.
– Sensation
– Evaluate perineal sensation to rule out any nerve compression or neuropathy.
– Gait Assessment
– Observe for any gait abnormalities that may contribute to pelvic floor dysfunction.
- Bimanual Pelvic Examination
Consent, ask to empty the bladder, light, gloves, sims and Cuscos self retaining bivalved speculum, prepare sponge forceps.
– Preparation
– Ensure patient comfort and privacy.
Positioning the Patient
– Use a lithotomy position or alternative position if mobility is limited.
– External Genitalia Inspection
– Look for vaginal atrophy, irritation, ulcers, or signs of infection.
– Assessment of Prolapse
– Ask the patient to bear down (Valsalva maneuver) to observe the degree of prolapse.
– Grade the prolapse using the Baden-Walker or POP-Q system.
– Internal Palpation
– Assess vaginal tone and pelvic floor muscle strength (e.g., by asking the patient to contract the muscles)-
Oxford grading scale – no contraction – 0
Flicker — 1
Weak —– 2
Moderate —3
Good—- 4
Strong —- 5
– Palpate for uterine size, mobility, and any adnexal masses.
– Stress Test:
– Perform a cough stress test to confirm urinary leakage.
– Speculum Examination
– Evaluate the vaginal walls for any anterior or posterior wall defects (e.g., cystocele or rectocele).
– Check for ulcers or discharge.
Sim Position to assess enterocele /small rectocele
First degree |
Cuscos speculum examination– Cervix- Healthy, Ulcers, oedema, bleeding, discharge. |
Sims speculum– Check for cystocele if not previously seen, Ask to strain and comment on the decent, Enterocele, rectocele |
VE– Reduce the prolapsed( lubricate well) and ask to cough. If incontinence- and do Boney’s test. Do VE |
Second degree(Beecham) |
cervix is seen, anteriorly- cyctocele. Posterior- rectocele. Cervix- Healthy, Ulcers, oedema, bleeding, discharge. |
Degree of prolapse. If 3rd degree- comment about the size. |
Sims speculum– Check for cystocele if not previously seen, Enterocele, rectocele |
VE– Reduce the prolapsed( lubricate well) and ask to cough. If incontinence- and do Boney’s test. Do VE |
PR– offer |
POP Q system
Comparison of the Classification Systems
Management
Step 1: Counseling
– Explain the Condition
– Describe uterovaginal prolapse and stress incontinence, their causes, and progression.
– Reassure the patient that these are treatable conditions.
– Discuss Goals of Treatment
– Improve quality of life, relieve symptoms, and restore pelvic anatomy and function.
– Inform About Treatment Options
– Outline surgical and non-surgical options, including their benefits, risks, and success rates.
– Address Patient Expectations
– Clarify her priorities (e.g., symptom relief, avoidance of surgery, or sexual function).
Step 2: Lifestyle Modifications
– Weight Loss
– Encourage weight reduction to decrease pressure on the pelvic floor.
– Avoid Straining
– Treat chronic constipation with high-fiber diets, hydration, and laxatives if needed.
– Smoking Cessation
– Reduces chronic cough, which worsens prolapse and incontinence.
– Manage Chronic Cough or Comorbidities
– Treat COPD, asthma, or other conditions contributing to increased intra-abdominal pressure.
Step 3: Investigations
– Bladder Diary
– Record fluid intake, frequency of urination, episodes of incontinence, and triggers over 3–7 days.
– Urodynamic Studies
– Assess bladder function and confirm stress incontinence.
– Rule out detrusor overactivity (urge incontinence) and mixed incontinence.
– Pelvic Ultrasound -TVS+ TAS
– Evaluate pelvic organ position, masses, and bladder post-void residual volume.
– Urine Analysis and Culture/UFR
– Rule out urinary tract infections.
– Blood Tests
– Check renal function (serum creatinine, electrolytes) if obstruction is suspected.
MANAGEMENT
Step 4: Non-Surgical Management
– Pelvic Floor Muscle Training (PFMT)
– Regular Kegel exercises, guided by a physiotherapist.
– Success Rate: Improves symptoms in 50-70% of mild cases.
– Pessary Use
– Vaginal devices to support pelvic organs, especially for women avoiding surgery.
– Requires regular cleaning and follow-ups.
– Success Rate: Symptom improvement in 70-90% with proper fitting.
Types Of Pessaries- Support pessary, Sapce occupying pessary
Support pessary- Ring , Smith, gehrung
Space occupying pessary- Gelhorn, Donut,Cube
How to measure pessary size
Line A: The vaginal length from posterior symphysis to apex or posterior fornix can be useful for sizing Ring, Donut and inflatable pessaries, or the length of a Gellhorn neck.
Line B: The vaginal width at the apex can be useful when considering the diameter of the Gellhorn, Dish, Shaatz.
Line C: The diameter of the introitus and vaginal shaft can help in measuring for the Cube.
– Lifestyle Adjustments (as above)
– Complement other treatments.
- lifestyle modifications
- limit fluid intake
- ↓ alcohol/caffeine intake
- stop smoking &
- ↓ weight if BMI ≥30
Step 5: Medical Management
– Vaginal Estrogen Therapy
– Indicated for postmenopausal women to improve vaginal tissue integrity.
– Success Rate: Alleviates mild prolapse symptoms and improves continence in ~50%.
– Medications for Incontinence (if mixed incontinence)
– Anticholinergics (e.g., oxybutynin) or beta-3 agonists (e.g., mirabegron).
– Success Rate: Effective in ~50-60% of patients with urgency components.
Step 6: Surgical Management
For Prolapse
- Vaginal Hysterectomy with Pelvic Floor Repair
– Standard surgery for uterine prolapse.
– Success Rate: ~80-90% long-term success.
- Sacrocolpopexy (with or without uterus sparing)
– Abdominal approach using mesh for suspension of the prolapsed uterus or vaginal cuff.
– Success Rate: >90% for symptom resolution.
-Route- open/laparoscopically
(POSTGRADUATE students must know about the steps of vaginal hysterectomy and how to handle the difficult cases)
- Sacrospinous Ligament Fixation
– Vaginal approach to fixate the prolapsed vaginal apex or uterus.
– Success Rate: ~85%.
- Colpocleisis (Vaginal Closure)
– For women who no longer desire vaginal intercourse.
– Success Rate: >95%, with minimal recurrence.
Types of Colpocleisis
- LeFort Colpocleisis
Partial closure of the vaginal canal with preservation of lateral channels for drainage.
- Complete Colpocleisis
Total closure of the vaginal canal without preserving any channels.
Preoperative Preparation
- Patient Selection
– Severe pelvic organ prolapse (e.g., stage III or IV POP-Q system).
– No desire for vaginal intercourse.
– No significant risk of cervical or uterine pathology (if uterus is retained).
- Preoperative Investigations
– Pap smear to rule out cervical pathology.
– Endometrial biopsy or ultrasound for uterine abnormalities if the uterus is retained.
– Urodynamic testing if urinary symptoms are present.
- Consent
– Explain loss of vaginal function and sexual intercourse.
– Discuss possible complications: bleeding, infection, urinary retention.
For Stress Incontinence
- Colposuspension (Burch Procedure)
– Lifts and supports the bladder neck and urethra.
– Success Rate: ~70-80%.
- Mid-Urethral Sling Procedure
– Retropubic (TVT) or trans obturator (TOT) approach.
– Success Rate: ~80-90%.
-Although its use is controversial, transvaginal mesh should be reserved for complex cases at high risk of failure, such as multicompartment /recurrent prolapse(TOG2023)
-it should only be used in the hands of trained and experienced surgeons.
- Bulking Agents (Injection)
– Less invasive, short-term results.
– Success Rate: ~40-60%.
Indications for bulking agents (injection synthetic material around urethra)
- Wishing to avoid major surgery/mesh
- Recurrent SUI after failed primary surgery
- Willing to accept less cure rate in favor of less invasive procedure with less risk of voiding difficulty
- Co-morbidities
- Desire future pregnancy
Inform all these women that
-
- Permanent material & may need repeat injections to have efficacy
- Lesser efficacy than alternate surgical procedures
- Poor durability Limited evidence on long-term efficacy & side effects
- NICE: give written information comprising agent name, manufacturer, injection date & surgeons details
Five agents currently available in UK
- Polyacrylamide hydrogel (Bulkamid)
- Polydimethlsiloxone
- Carbon beads
- Calcium hydroxyapatite
- Cross linked vinyl dimethyl polydimethylsiloxane
Mechanism of action
- Intramural bulking agents creat additional submucosal bulk by providing artificial mucosal cushion & help in coaptation (adaption of urethral muscles to remain closed at rest)
- The ideal bulking agent should be
- easy to inject,
- retain volume and durability,
- be biocompatible with minimal inflammatory and fibrotic response.
- no migration from the site of injection (normally meaning particles with a diameter of >80 μm suspended in a gel).
There is no ideal bulking agent
Step 7: Post-Operative Care and Follow-Up
– Early Recovery
-Antibiotics for 1 week
-Avoid constipation for 2weeks -lactulose for 1 week
-Avoid bathing in pools for 1 month
– Avoid heavy lifting and straining for 3months
– Resume light physical activity as tolerated.
-can have sexual intercourse after one month whenever she feels comfortable
– Long-Term Care
– Reinforce pelvic floor muscle exercises.
– Regular follow-ups for pessary care or to monitor for recurrence.